Counsyl Prelude™ Prenatal Screen

Non-invasive insight into your baby’s development

Counsyl Prelude Prenatal Screen patients

As early as week 10, find out if your baby has an increased chance for chromosome conditions like Down syndrome.

Lacey O., expecting her first baby girlCounsyl Prelude Prenatal Screen patient

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CounsylCounsyl Prelude™ Prenatal Screen

  • A clock

    Early screening

    The Counsyl Prelude™ Prenatal Screen can be done as early as 10 weeks into your pregnancy and can reduce the need for invasive tests like amniocentesis.

    See what we test for
  • A stethoscope

    Trusted by top doctors

    Counsyl has screened hundreds of thousands of people, and we work directly with a network of over 6,000 health care professionals.

    Hear from our patients
  • An umbrella

    Covered by insurance

    The Counsyl Prelude Prenatal Screen is covered by most major insurance companies. Chances are yours is one of them.

    Learn more about Counsyl billing


Chromosome conditions happen by chance and aren't usually inherited

Usually babies have 46 chromosomes—23 from each parent. Occasionally, a baby will have an extra or a missing chromosome. These changes can lead to developmental conditions like Down syndrome or Turner syndrome. Using a simple blood draw from the mother, the Prelude Prenatal Screen looks for evidence of an extra or missing chromosome that may affect a baby’s health.

If you’re interested in knowing, this test can also be used to predict the sex of your baby.

Genetic screening illustration
The Counsyl Kit


We can look for a variety of conditions

The Prelude Prenatal Screen looks for the most serious chromosome conditions, including Down syndrome (Trisomy 21), Edward's Syndrome (Trisomy 18), and Patau Syndrome (Trisomy 13).

Your doctor or healthcare provider can help decide whether you should screen for conditions that aren’t as serious or aren’t as common, including too many or too few sex chromosomes and microdeletions.

View full list

Why get tested?

Knowing your risks can help you be ready

If your screen turns up something unusual, your doctor or healthcare provider will offer a follow-up diagnostic procedure to confirm the result.

  • CVS (chorionic villus sampling)

    Before the 14th week of your pregnancy, a doctor can take a small sample of your placenta to confirm the result of the Prelude Prenatal Screen.

  • Amniocentesis

    Between the 16th and 22nd week of your pregnancy, a doctor can take a small sample of fluid from your uterus to confirm the result of the Prelude Prenatal Screen.

  • Preparation

    Whether or not you have a more invasive diagnostic procedure, you can learn about your options from one of our genetic counselors, so you can feel confident you’re making the best decision for you.


Lacey & Sejin's story

Lacey, Counsyl Prelude Prenatal Screen patient
Taking it has helped me sleep better because getting answers - one way or the other - is a huge relief.Lacey, 32 (pictured with fiancé Sejin)Counsyl patient, expecting her first baby girl
Lacey holding a lemon
Lacey and her fiancé Sejin
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Our process

Get the conversation started with your doctor today

You can get the Prelude Prenatal Screen as early as 10 weeks into pregnancy.

  • Stethoscope

    Talk to your doctor

    Ask your doctor or healthcare provider to order the Prelude Prenatal Screen.

  • Blood tube

    Have your blood drawn

    Your doctor or healthcare provider will send the sample directly to us.

  • Results document

    Get your results in ~1 week

    Results from the Prelude Prenatal Screen are available in about one week, and you can access them online.

  • Counselor

    Talk with an expert

    Our genetic counselors are here for you to answer questions and make sure you have all the resources you need.


We have you covered

From insurance coverage to financial assistance, we work hard to make testing accessible.

Learn more about how we can help


Talk with a genetic specialist

Board certified genetic counselors are available to answer your questions before and after testing.

Talk with a genetic counselor


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